Impact of CFTR MSD2 Mutations (R1158, R1030, W846) on Channel Activity and cAMP-Independent Activation
Publisher：Unknown
·Published at: 2025-12-13
Discussion regarding how mutations of specific basic and aromatic amino acids in the membrane-spanning domain 2 (MSD2) of CFTR, specifically R1158, R1030, and W846, affect channel activity and facilitate cAMP-independent activation by potentiators.
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