Impact of NBD1 Structural Defects and Proteostasis on CFTR Corrector Responsiveness
发布者：Unknown
·发布于: 2025-12-13
A discussion regarding how structural defects in the nucleotide-binding domain 1 (NBD1) and interactions with proteostasis pathways contribute to the differential responsiveness of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) variants to small-molecule correctors.